Will be second nature in a few days, don't like how everything seems greyed out though and the traffic lights changing is like moving a blind hamsters food bowl. But other than that, no real difference..
You can get the colour back if your on a Mac.
http://modmyi.com/forums/mac-news/727795-how-put-color-back-into-itunes-10-a.html
Its bad, check out the new visualisations