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Havent used AO48 but have used 888's with a mix of soft and medium and as you said medium on front and soft on the back is the way to go.
However I would ( and have ) reversed this set up in wet conditions though ( very wet cadwell park ).
Medium front soft back Ao48s is what my Dad runs as a permanent set up on his R5 race car.
Perfectly ok to mix compounds front and rear and you may even find like we did this is a much better way to go in terms of tyre wear and also lap times.