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to reduce grain keep the ISO as low as possible (100), you are best to use a tripod at night, if you set the aperture to a large f number (f22) then it will make the street lights appear as starbursts rather than just flare.
you are best to shoot on aperture priority then just adjust the exposure compensation (+/-) according to the situation
If you cant get hold of a tripod you will probably have to run at a high ISO to get any usable shots.
If you can get hold of one, then you can experiment with some longer shutter speeds which will give you great results.
If you think your going to start doing a lot of lower light shooting I would really look in to getting a faster bit of glass. The 50mm F1.8 can be had for less that £80.
At f1.8 and medium iso you should be able to get some crisp hand held shots (for future reference!)
Tripod, ISO 100, then as long as nothing is moving pick a suitable aperture for your desired depth of field and shutter speed.
Most important thing is to nail the White Balance, street lights give nasty yellow colour cast. I've never done it myself but learning how to set a custom white balance or nailing it in RAW could give the best results.