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What kind of speakers you looking for? Just front hifi speakers or full surround?
For hifi: Wharfedale Diamond 9.1 (£150 new) or Tannoy Mercury F1 (£109 new). These are best I can think of from a couple months ago. Best check what hi-fi mag and check in the buyers guide at the back for lastest. The two i mentioned are very highly rated and you should be able to get them around your price range 2nd hand or not much more new (prices above RRP i think).
ps. try what hifi forum at http://whathifi.com/forums/5.aspx. Thats the 'hifi' section, post ur Qs there and editors normally get back to you as well as other ppl in the know.