Put very very simply.
Ecotek makes a hiss because as Jones said, its air being sucked in. Its not that there is a vacuum inside the inlet manifold, but that there is a lower relative pressure than outside it, and air flows from high to low pressure.
On an NA car there is always 14.7lbs of pressure acting on the throttle plate. At wide open throttle you have effectively 1 bar of boost, but thats only because its the natural ambeint air pressure.
Turbos have a dump valve to release excess pessure before the throttle plate.....it wont create any mechanical damage to the throttle itself or the engine, but it will annoy your turbo. So the hiss comes from the high pressure in the plumbing of a turbo engine, excaping to the outside which has a lower ambeint pressure. If you had a DV on a NA engine you wouldnt get a hiss even though there is a pressure on the throttle plate simple because the pressure inside the airbox trunking before the throttle plate is the same as that outside it. That equals no movement between those two areas.
simeple eh!